The scientific objetives are focused on the following topics:
Preparation and characterization of botanical and fungal biopesticides
Database and extract library: selective bioprospecting of plant and fungal endophytes. Screening their microextract activity against insect pests, nematodes and fungal pathogens. Metabolomic profiles. Identification of the active components and quantification of their activity.
Optimization (chemical and biotechnological processes) of biopesticides: fungal biotransformations, biomimetic transformations and / or supercritical extraction.
Biotechnological production: artificial-biotech crops (aeroponic, in vitro) of pre-selected plant species based on their bioactivity. Fermentation of endophytes producing active metabolites.
Technology transfer: Plant Variety Registration and deposit of selected fungal strains. Patents (extracts / bioactive products, chemical processing and / or biotech formulations) in collaboration with other entities. Transfer of results through patent licensing options and / or trade secret.
Patent transfer to ECOFLORA AGRO of bioactive extracts and essential oils from a cultivated experimentally variety of wormwood.
Review on the nematicidal activity of essential oils against the two major groups of pathogenic importance nematodes: Meloidogyne spp and Bursaphelenchus xylophilus.
M. F. Andres, A. Gonzalez-Coloma, J. Sanz, J. Burillo, P. Sainz (2012). Nematicidal activity of essential oils: a review. Phytochem. Rev. 11: 371-390.
Biotechnological production of plant biomass from an endemic and endangered species for the production of extracts and bioactive compounds.
B. M. Fraga, C. E. Díaz, L. J. Amador, M. Reina, O. Santana, A. González-Coloma (2014). Bioactive compounds from transformed root cultures and aerial parts of Bethencourtia hermosae. Phytochemistry 108, 220–228.
Chemical characterization of active supercritical CO2 extracts from an endemic Iberian aromatic plant experimentally cultivated.
L. F. Julio, L. Martín, R. Muñoz, A. M. Mainar, J. S.Urieta, j. Sanz, J. Burillo, A. González-Coloma (2014). Comparative chemistry and insect antifeedant effects of conventional (Clevenger and Soxhlet) and supercritical extracts (CO2) of two Lavandula luisieri populations. Ind. Crop. Prod. 58, 25–30.